ErythronDB

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ErythronDB offers a collection of searches that you can uses to generate lists of genes or browses sets of gene-interactions (relationships) by matching various criteria (official identifiers, patterns of expression, differential expression). These lists can be combined as steps in a search strategy to build complex questions.

Gene Name or Identifier

Identifier List View ErythronDB expression data and related details about a gene or list of genes of interest.
MGI, EntrezGene, or ENSEMBL Identifier Find genes by exact match to official gene symbol, EntrezGene Identifier, MGI Identifier, or ENSEMBL Identifier.
Keyword Find genes by matching the provided text to gene names, symbols, and synonyms.

Gene Annotation

GO Term Identify genes that correspond to a GO identifier or term.
KEGG Pathway Identify genes expressed in erythrocyte development that are involved in the specified pathway.
Tissue Specificity Identify genes that have specific or non-specific expression patterns in adult mouse tissues.
Potential Contaminants Identify genes marked as likely contaminants in specific lineage samples.
Known Erythroid Genes A manually curated lists of genes relevant to erythroid function and erythropoiesis.

Pattern of mRNA Expression

Minimum Expression Level Find genes expressed at levels above a specified threshold in an erythropoietic lineage.
Stage in which Minimally or Maximally Expressed Find genes that are maximally or minimally expressed in a specified cell stage during erythroid differentiation.
Shape of Expression Profile Find genes that exhibit a characteristic pattern of expression during development within a sepecified erythropoeitic lineage.
Not Expressed Find genes not expressed during specific erythropoietic lineages or not documented in ErythronDB.

Differential Expression

Between Cell Stages Find genes differentially expressed between pairs of developmental cell-stages within a specified erythropoietic lineage.
Equivalent Cell Stages Across Lineages Find genes differentially expressed between equivalent cell-stages across erythropoietic lineages.

Transcriptional Regulation

Predicted Transcription Factor Targets Identify genes that have been computationally predicted to be common transcription factor targets.
Transcription Factor Targets from ChIP Analysis Find targets of key erythroipoietic transcription factors based on results from published ChIP-Seq studies.

Relationships

Gene Neighborhood Search for genes that have an inferred functional association with a specific gene of interest.
Upload or Enter Gene List Search for relationships among multiple genes of interest.
Supported by KEGG Pathway Find ErythronDB relationships that are also present in a KEGG Pathway.

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