The frequency matrix for alternative (not muscle gene)  sp-1 sites...

  2.0  0.0  1.0  0.0  0.0  1.0  0.0  0.0  2.0  0.0  0.0
  1.0  0.0  0.0  0.0  0.0  7.0  0.0  1.0  2.0  1.0  6.0
  6.0  6.0  9.0 10.0 10.0  0.0 10.0  9.0  6.0  8.0  1.0
  1.0  4.0  0.0  0.0  0.0  2.0  0.0  0.0  0.0  1.0  3.0


The resulting weight matrix...


 -0.24 -2.06 -0.88 -2.06 -2.06 -0.88 -2.06 -2.06 -0.24 -2.06 -2.06
 -0.88 -2.06 -2.06 -2.06 -2.06  1.24 -2.06 -0.88 -0.24 -0.88  1.05
  1.05  1.05  1.57  1.71  1.71 -2.06  1.71  1.57  1.05  1.42 -0.88
 -0.88  0.54 -2.06 -2.06 -2.06 -0.24 -2.06 -2.06 -2.06 -0.88  0.20




The frequency matrix was generated by aligning the sp-1 sites 
within the following list using a Gibbs sampling algorithim.  

 
> human cyp21b   M12793
agggccactctgtgggtgggtcggtgggaa ggcacctgag
> human egfr   X06370
ggcaccgctcccctcccatgcgccgccccactcccgccg
> M17704 Porcine growth hormone gene.           
ggaacaggatgagtgggaggaggttctaaattatccatta
> Mouse tissue plasminogen activator gene,    M26065
 ccccgcccacacctctggccccaccccttcttcatccttc 
> mouse thymidylate synthase   M29309
gctgtaaccacttctgtcacgtgggggcggggtctgccac
> Rat transforming growth factor alpha (TGF-alpha), M31075
cagtgccaccgggaggcgcggtcgtccctccgcccgcgcg
> human aldolase A   X12447
tggctcgcctctcgggggcggcccgtagcccagtccgtcg
> SV-40-III   J02400 
atgggcggaactgggcggagttaggggcgggatgggcgga
> HSV-IE-3-III  Herpes simplex virus (HSV) type 1  X14112 
gatggcgcggatgggcggggccgggggttcgaccaacggg
> human dhfr   X00855
gtgcgccggggcgggggggcggggcctcgcctgcacaaat